Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50029460
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284753((R)-N*1*-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-e...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284753((R)-N*1*-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-e...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284755(2-[(Formyl-hydroxy-amino)-methyl]-4-methyl-pentano...)
Affinity DataKi:  1nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284755(2-[(Formyl-hydroxy-amino)-methyl]-4-methyl-pentano...)
Affinity DataKi:  2nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284754((S)-2-Mercaptomethyl-4-methyl-pentanoic acid ((S)-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  3nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284753((R)-N*1*-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-e...)
Affinity DataKi:  3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284751([(S)-4-Methyl-2-((S)-9-oxo-1,8-diaza-tricyclo[10.6...)
Affinity DataKi:  4nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284753((R)-N*1*-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-e...)
Affinity DataKi:  5nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284751([(S)-4-Methyl-2-((S)-9-oxo-1,8-diaza-tricyclo[10.6...)
Affinity DataKi:  5nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086884(N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO...)
Affinity DataKi:  9nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284751([(S)-4-Methyl-2-((S)-9-oxo-1,8-diaza-tricyclo[10.6...)
Affinity DataKi:  14nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  14nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284755(2-[(Formyl-hydroxy-amino)-methyl]-4-methyl-pentano...)
Affinity DataKi:  15nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284755(2-[(Formyl-hydroxy-amino)-methyl]-4-methyl-pentano...)
Affinity DataKi:  18nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284750((R)-2-[(S)-3-Methyl-1-((S)-9-oxo-1,8-diaza-tricycl...)
Affinity DataKi:  20nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  25nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284751([(S)-4-Methyl-2-((S)-9-oxo-1,8-diaza-tricyclo[10.6...)
Affinity DataKi:  78nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284752({(S)-2-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-eth...)
Affinity DataKi:  102nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284754((S)-2-Mercaptomethyl-4-methyl-pentanoic acid ((S)-...)
Affinity DataKi:  114nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  115nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284757((R)-3-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-ethy...)
Affinity DataKi:  163nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284757((R)-3-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-ethy...)
Affinity DataKi:  171nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284752({(S)-2-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-eth...)
Affinity DataKi:  300nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284752({(S)-2-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-eth...)
Affinity DataKi:  432nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284757((R)-3-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-ethy...)
Affinity DataKi:  472nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284757((R)-3-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-ethy...)
Affinity DataKi: >620nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284754((S)-2-Mercaptomethyl-4-methyl-pentanoic acid ((S)-...)
Affinity DataKi: >800nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284751([(S)-4-Methyl-2-((S)-9-oxo-1,8-diaza-tricyclo[10.6...)
Affinity DataKi:  806nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  850nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284752({(S)-2-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-eth...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284758((2S,3R)-5-Methyl-3-((S)-1-methylcarbamoyl-2-phenyl...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284750((R)-2-[(S)-3-Methyl-1-((S)-9-oxo-1,8-diaza-tricycl...)
Affinity DataKi:  3.23E+3nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284752({(S)-2-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-eth...)
Affinity DataKi:  6.58E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284750((R)-2-[(S)-3-Methyl-1-((S)-9-oxo-1,8-diaza-tricycl...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article