Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50029455
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]LTD4 from receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50004633(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-imidaz...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]ligand from platelet activating factor (PAF) receptor in rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]LTD4 from receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]ligand from platelet activating factor (PAF) receptor in rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284691(CP-95492 | 2-(2-{3-[4-(2-Methyl-imidazo[4,5-c]pyri...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]ligand from platelet activating factor (PAF) receptor in rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]LTD4 from receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]ligand from platelet activating factor (PAF) receptor in rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284691(CP-95492 | 2-(2-{3-[4-(2-Methyl-imidazo[4,5-c]pyri...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]LTD4 from receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50004633(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-imidaz...)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]LTD4 from receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ligand from platelet activating factor (PAF) receptor in rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article