Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50029396
TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  15nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]U-86170)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041959(CHEMBL27441 | (5-Methoxy-1-methyl-1,2,3,4-tetrahyd...)
Affinity DataKi:  26nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284086(Trifluoro-methanesulfonic acid (5S,6R)-6-dipropyla...)
Affinity DataKi:  40nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  48nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041959(CHEMBL27441 | (5-Methoxy-1-methyl-1,2,3,4-tetrahyd...)
Affinity DataKi:  117nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284086(Trifluoro-methanesulfonic acid (5S,6R)-6-dipropyla...)
Affinity DataKi:  121nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041959(CHEMBL27441 | (5-Methoxy-1-methyl-1,2,3,4-tetrahyd...)
Affinity DataKi:  145nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]U-86170)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 5A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  168nMAssay Description:Binding affinity was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]8-OH-DPAT )More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284083(Trifluoro-methanesulfonic acid (5S,6R)-5-methyl-6-...)
Affinity DataKi:  171nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284084((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  253nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 5A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284084((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  287nMAssay Description:Binding affinity was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]8-OH-DPAT )More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284086(Trifluoro-methanesulfonic acid (5S,6R)-6-dipropyla...)
Affinity DataKi:  546nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]U-86170)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284083(Trifluoro-methanesulfonic acid (5S,6R)-5-methyl-6-...)
Affinity DataKi:  621nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284084((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  1.59E+3nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284082((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi: >1.79E+3nMAssay Description:Binding affinity was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]8-OH-DPAT )More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284084((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  2.33E+3nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]U-86170)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 5A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041959(CHEMBL27441 | (5-Methoxy-1-methyl-1,2,3,4-tetrahyd...)
Affinity DataKi:  2.33E+3nMAssay Description:Binding affinity was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]8-OH-DPAT )More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284083(Trifluoro-methanesulfonic acid (5S,6R)-5-methyl-6-...)
Affinity DataKi:  2.56E+3nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]U-86170)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 5A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284083(Trifluoro-methanesulfonic acid (5S,6R)-5-methyl-6-...)
Affinity DataKi:  3.07E+3nMAssay Description:Binding affinity was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]8-OH-DPAT )More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 5A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284086(Trifluoro-methanesulfonic acid (5S,6R)-6-dipropyla...)
Affinity DataKi: >3.45E+3nMAssay Description:Binding affinity was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]8-OH-DPAT )More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284085((5S,6R)-6-Dipropylamino-5-methyl-5,6,7,8-tetrahydr...)
Affinity DataKi:  5.04E+3nMAssay Description:Binding affinity was measured at 5-HT1A receptor in rat striatal membranes using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284085((5S,6R)-6-Dipropylamino-5-methyl-5,6,7,8-tetrahydr...)
Affinity DataKi:  6.67E+3nMAssay Description:Binding affinity was measured from rat striatal membrane using [3H]-spiperone at D2 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284087((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  6.72E+3nMAssay Description:Binding affinity was measured at 5-HT1A receptor in rat striatal membranes using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284082((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Affinity DataKi:  1.67E+4nMAssay Description:Binding affinity was measured from rat striatal membrane using [3H]-spiperone at D2 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article