Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50029303
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283109(5,5-Diphenyl-3-[6-(4-phenyl-piperidin-1-yl)-hexyl]...)
Affinity DataKi:  3nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283109(5,5-Diphenyl-3-[6-(4-phenyl-piperidin-1-yl)-hexyl]...)
Affinity DataKi:  3nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  6nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50283108(5,5-Diphenyl-3-[4-(4-phenyl-piperidin-1-yl)-butyl]...)
Affinity DataKi:  8.40nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283108(5,5-Diphenyl-3-[4-(4-phenyl-piperidin-1-yl)-butyl]...)
Affinity DataKi:  10nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283107(5,5-Diphenyl-3-[6-(4-phenyl-piperazin-1-yl)-hexyl]...)
Affinity DataKi:  11nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283107(5,5-Diphenyl-3-[6-(4-phenyl-piperazin-1-yl)-hexyl]...)
Affinity DataKi:  13nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283112(5,5-Diphenyl-3-[2-(4-phenyl-piperidin-1-yl)-ethyl]...)
Affinity DataKi:  17nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283114(5,5-Diphenyl-3-[5-(4-phenyl-piperazin-1-yl)-pentyl...)
Affinity DataKi:  19nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283114(5,5-Diphenyl-3-[5-(4-phenyl-piperazin-1-yl)-pentyl...)
Affinity DataKi:  19nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283111(5,5-Diphenyl-3-[3-(4-phenyl-piperidin-1-yl)-propyl...)
Affinity DataKi:  22nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283111(5,5-Diphenyl-3-[3-(4-phenyl-piperidin-1-yl)-propyl...)
Affinity DataKi:  25nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283112(5,5-Diphenyl-3-[2-(4-phenyl-piperidin-1-yl)-ethyl]...)
Affinity DataKi:  43nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283113(5,5-Diphenyl-3-[4-(4-phenyl-piperazin-1-yl)-butyl]...)
Affinity DataKi:  49nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  70nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  107nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50002238(1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)pi...)
Affinity DataKi:  164nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50002238(1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)pi...)
Affinity DataKi:  265nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283113(5,5-Diphenyl-3-[4-(4-phenyl-piperazin-1-yl)-butyl]...)
Affinity DataKi:  328nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  562nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283110(5,5-Diphenyl-3-[2-(4-phenyl-piperazin-1-yl)-ethyl]...)
Affinity DataKi:  664nMAssay Description:Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H](+)-PENTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283110(5,5-Diphenyl-3-[2-(4-phenyl-piperazin-1-yl)-ethyl]...)
Affinity DataKi:  842nMAssay Description:Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article