Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50021404
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640301(CHEMBL5565952)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50595204(CHEMBL4451085)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 44nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50595204(CHEMBL4451085)
Affinity DataIC50: 45nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 89nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human HDAC3 using fluorogenic Boc-Lys (aetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50595204(CHEMBL4451085)
Affinity DataIC50: 125nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 145nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human HDAC3 (379 to 382 residues) using (Arg-His-Lys-Lys(Ac)) as substrate incubated for 60 mins by HDAC-Glo I/II chemiluminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human HDAC1 using fluorogenic Boc-Lys (aetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50595204(CHEMBL4451085)
Affinity DataIC50: 379nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640300(CHEMBL5568268)
Affinity DataIC50: 390nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human HDAC1 (379 to 382 residues) using (Arg-His-Lys-Lys(Ac)) as substrate incubated for 60 mins by HDAC-Glo I/II chemiluminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50595204(CHEMBL4451085)
Affinity DataIC50: 530nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Blood fluke)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 750nMAssay Description:Inhibition of Schistosoma mansoni HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50595204(CHEMBL4451085)
Affinity DataIC50: 828nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50565135(CHEMBL4777961)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC11 transfected in HEK293T cells using Ac-ETDKrnyr-AMC as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163624(SR-3208 | US10807944, Compound RLS2-131 | US117319...)
Affinity DataIC50: 880nMAssay Description:Inhibition of human HDAC2 using fluorogenic Boc-Lys (aetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640299(CHEMBL5561545)
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC11 transfected in HEK293T cells using Ac-ETDKrnyr-AMC as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human HDAC8 using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640300(CHEMBL5568268)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640300(CHEMBL5568268)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640300(CHEMBL5568268)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of human HDAC8 (379 to 382 residues) using (Arg-His-Lys-Lys(Ac)) as substrate incubated for 60 mins by HDAC-Glo I/II chemiluminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640300(CHEMBL5568268)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 7.11E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic-(RHKKAc) as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640301(CHEMBL5565952)
Affinity DataIC50: 8.96E+3nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 9.09E+3nMAssay Description:Inhibition of human HDAC6 (379 to 382 residues) using (Arg-His-Lys-Lys(Ac)) as substrate incubated for 60 mins by HDAC-Glo I/II chemiluminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50640302(CHEMBL5557078)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor-de-Lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human HDAC10 (379 to 382 residues) using (Arg-His-Lys-Lys(Ac)) as substrate incubated for 60 mins by HDAC-Glo I/II chemiluminescence as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM163619(UF010 | US10807944, Compound UF010 | US11731934, C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Universidade de Lisboa

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed