Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50021891
Displayed 1 to 50 (of 65 total ) | Next | Last >>
Affinity DataEC50: 31nMAssay Description:Binding affinity to yeast Pho85 pretreated with yeast lysates for 45 mins followed by incubation with Kinobead-Sepharose affinity matrix slurry for 3...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 330nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 570nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 610nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue treated for 4 hrs followed by drug wash-out and...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 870nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue treated for 4 hrs followed by drug wash-out and...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 990nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue measured after 120 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue measured after 18 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.62E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of human full length CDK2 (1 to 298 residues)/N-terminal GST-tagged Cyclin E1 (1 to 410 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 2.89E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Reversible inhibition of human full length CDK2 (1 to 298 residues)/N-terminal GST-tagged Cyclin E1 (1 to 410 residues) expressed in baculovirus expr...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 3.40E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 4.30E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 4.90E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 5.25E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 5.36E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 5.76E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 6.10E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 6.30E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 6.50E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Reversible inhibition of human full length CDK1 (1 to 297 residues)/N-terminal GST-fused Cyclin B1 (1 to 433 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 8.00E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Reversible inhibition of human full length CDK2 (1 to 298 residues)/N-terminal GST-tagged Cyclin E1 (1 to 410 residues) expressed in baculovirus expr...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Reversible inhibition of human full length CDK7 (1 to 346 residues)/N-terminal GST-fused Cyclin H (1 to 323 residues)/MAT1 (1 to 309 residues) expres...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.16E+4nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.22E+4nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.64E+4nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.77E+4nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Reversible inhibition of human full length CDK1 (1 to 297 residues)/N-terminal GST-fused Cyclin B1 (1 to 433 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 2.20E+4nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 2.66E+4nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
LifeMine Therapeutics
Curated by ChEMBL
LifeMine Therapeutics
Curated by ChEMBL
Affinity DataEC50: 3.02E+4nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair




3D Structure (crystal)










