Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50021547
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641865(CHEMBL5571927)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataKi:  5.40E+3nMAssay Description:Binding affinity of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) assessed as inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641860(CHEMBL5575894)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641863(CHEMBL5575943)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641864(CHEMBL5566786)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641862(CHEMBL5568733)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641861(CHEMBL5575533)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bcl-2 (unknown origin) incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mcl-1 (unknown origin) incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641855(CHEMBL5573405)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641854(CHEMBL5567148)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641853(CHEMBL5575216)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bcl-xl (unknown origin) incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641859(CHEMBL5569235)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641858(CHEMBL5592005)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641857(CHEMBL5569964)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641856(CHEMBL5571460)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed