Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50021782
TargetKelch-like ECH-associated protein 1(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50180850(CHEMBL3819587)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to KEAP1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPolycomb protein EED(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM291687(US9580437, Example 2 | N-((5-Fluoro-2,3-dihydroben...)
Affinity DataIC50: 26nMAssay Description:Inhibition of EED (unknown origin) by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50644834(CHEMBL5571297)
Affinity DataKd:  90nMAssay Description:Binding affinity to VHL (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)
Affinity DataKd:  185nMAssay Description:Binding affinity to VHL (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50644835(CHEMBL5566038)
Affinity DataKd:  360nMAssay Description:Binding affinity to KLHDC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)