Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50019793
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50097721(CHEMBL1879790 | EN300-11843)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM625991(EN300-11760)
Affinity DataIC50: 28nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50623066(CHEMBL165728)
Affinity DataIC50: 34nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM626151(EN300-34927)
Affinity DataIC50: 45nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50623067(CHEMBL5393918)
Affinity DataIC50: 50nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50053610(2-(3-Chloro-phenyl)-ethylamine | 2-(3-chlorophenyl...)
Affinity DataIC50: 52nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM10999(CHEMBL522 | Benzenemethanamine | phenylmethanamine...)
Affinity DataIC50: 61nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM626112(EN300-231127)
Affinity DataIC50: 62nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50623068(3-Fluoro-Benzylamine | CHEMBL12722)
Affinity DataIC50: 71nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50623069(CHEMBL5429989)
Affinity DataIC50: 77nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50159267(2-p-Tolyl-ethylamine | 2-(4-methylphenyl)ethylamin...)
Affinity DataIC50: 77nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM626141(EN300-32113)
Affinity DataIC50: 81nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM626032(EN300-16560)
Affinity DataIC50: 982nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed