Compile Data Set for Download or QSAR
Report error Found 220 Enz. Inhib. hit(s) with all data for entry = 50019764
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622852(CHEMBL5412458)
Affinity DataIC50: 79nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622861(CHEMBL5396862)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622890(CHEMBL5435509)
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622855(CHEMBL5418291)
Affinity DataIC50: 152nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622854(CHEMBL5401324)
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622860(CHEMBL5422115)
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622872(CHEMBL5415322)
Affinity DataIC50: 330nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622869(CHEMBL5416853)
Affinity DataIC50: 420nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622870(CHEMBL5415248)
Affinity DataIC50: 420nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622853(CHEMBL5399780)
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622837(CHEMBL5439360)
Affinity DataIC50: 440nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622849(CHEMBL5408173)
Affinity DataIC50: 440nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622856(CHEMBL5406488)
Affinity DataIC50: 740nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622871(CHEMBL5397410)
Affinity DataIC50: 970nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622839(CHEMBL1229862)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622888(CHEMBL5433170)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622891(CHEMBL5440118)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622836(CHEMBL5401412)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622852(CHEMBL5412458)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate and 100 nM HDAC8 preincubated for 1 hr followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622873(CHEMBL5430419)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622840(CHEMBL5403885)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622797(CHEMBL5431465)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622865(CHEMBL5440898)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622889(CHEMBL5433087)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622848(CHEMBL5434144)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622852(CHEMBL5412458)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of HDAC8 C102S/C153S/C131S triple mutant (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622851(CHEMBL5436404)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622858(CHEMBL5417754)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622852(CHEMBL5412458)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HDAC8 C102S/C153S/C275S triple mutant (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622859(CHEMBL5399226)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622793(CHEMBL4546345)
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622843(CHEMBL5404196)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622845(CHEMBL5412663)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622863(CHEMBL5422346)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622893(CHEMBL5439733)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622838(CHEMBL3273124)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622830(CHEMBL4569890)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622847(CHEMBL5396586)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622842(CHEMBL5400766)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622855(CHEMBL5418291)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HDAC8 C102S/C153S/C131S triple mutant (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622861(CHEMBL5396862)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate and 100 nM HDAC8 preincubated for 1 hr followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622870(CHEMBL5415248)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate and 100 nM HDAC8 preincubated for 1 hr followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622846(CHEMBL5413048)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622885(CHEMBL5434827)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622852(CHEMBL5412458)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of HDAC8 C102S/C153S/C352S triple mutant (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622887(CHEMBL5415067)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622855(CHEMBL5418291)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HDAC8 C102S/C153S/C352S triple mutant (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622844(CHEMBL5438923)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622856(CHEMBL5406488)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate and 100 nM HDAC8 preincubated for 1 hr followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM50622794(CHEMBL4547890)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
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