Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50020051
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50: >2.00E+5nMAssay Description:Activation of wildtype CFTR G551D mutant (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625832(CHEMBL5425003)
Affinity DataEC50:  2.00E+3nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625831(CHEMBL5413245)
Affinity DataEC50:  400nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625830(CHEMBL4089490)
Affinity DataEC50:  70nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625829(CHEMBL5417364)
Affinity DataEC50:  385nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625828(CHEMBL5425079)
Affinity DataEC50:  571nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625827(CHEMBL5407009)
Affinity DataEC50:  377nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50541010(CHEMBL4637667)
Affinity DataEC50:  340nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM48611(cid_646403 | SMR000014090 | N-[5-[(3,4-dimethoxyph...)
Affinity DataEC50:  685nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625826(CHEMBL5412406)
Affinity DataEC50:  332nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232949(CHEMBL4100901)
Affinity DataEC50:  251nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237277(CHEMBL4086433)
Affinity DataEC50:  138nMAssay Description:Activation of human CFTR expressed in rat FRT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139827(5-Butyl-7-chloro-6-hydroxy-pyrido[1,2-a]quinolinyl...)
Affinity DataEC50:  750nMAssay Description:Activation of wildtype CFTR G551D mutant (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataEC50:  4.50E+4nMAssay Description:Activation of wildtype CFTR in human Calu-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139822(10-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; ch...)
Affinity DataEC50: >2.00E+5nMAssay Description:Activation of wildtype CFTR G551D mutant (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50032694(CHEMBL3354672)
Affinity DataEC50:  2.10E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625824(CHEMBL5429576)
Affinity DataEC50:  70nMAssay Description:Activation of CFTR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139827(5-Butyl-7-chloro-6-hydroxy-pyrido[1,2-a]quinolinyl...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of wildtype CFTR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50:  1.46E+5nMAssay Description:Activation of wildtype CFTR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139822(10-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; ch...)
Affinity DataEC50:  1.41E+5nMAssay Description:Activation of wildtype CFTR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625823(CHEMBL5420411)
Affinity DataEC50:  2.90E+3nMAssay Description:Activation of wildtype CFTR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625822(CHEMBL5428049)
Affinity DataEC50:  2.10E+3nMAssay Description:Activation of wildtype CFTR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625821(CHEMBL5437717)
Affinity DataEC50:  1.00E+5nMAssay Description:Activation of wildtype CFTR in human Calu-3 cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625825(CHEMBL5423437)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity at human wildtype CFTR assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataKi:  4.80E+3nMAssay Description:Binding affinity at human wildtype CFTR assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed