Compile Data Set for Download or QSAR
Report error Found 125 Enz. Inhib. hit(s) with all data for entry = 50020565
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631296(CHEMBL5397297)
Affinity DataEC50:  71nMAssay Description:Inhibition of STAT1 phosphorylation in human SK-MES-1 cells pretreated for 30 mins followed by IL-6 stimulation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631296(CHEMBL5397297)
Affinity DataEC50:  89nMAssay Description:Inhibition of STAT3 phosphorylation in human SK-MES-1 cells pretreated for 30 mins followed by IL-6 stimulation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631296(CHEMBL5397297)
Affinity DataEC50:  90nMAssay Description:Inhibition of STAT3 phosphorylation in human SK-MES-1 cells pretreated for 30 mins followed by GM-CSF stimulation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631296(CHEMBL5397297)
Affinity DataEC50:  40nMAssay Description:Inhibition of STAT5 phosphorylation in human SK-MES-1 cells pretreated for 30 mins followed by GM-CSF stimulation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631296(CHEMBL5397297)
Affinity DataIC50: 0.0440nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631288(CHEMBL5398372)
Affinity DataIC50: 0.563nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631308(CHEMBL5413283)
Affinity DataIC50: 0.577nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631297(CHEMBL5423944)
Affinity DataIC50: 0.637nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631294(CHEMBL5405043)
Affinity DataIC50: 0.799nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631289(CHEMBL5408324)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631292(CHEMBL5410919)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631307(CHEMBL5393770)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631280(CHEMBL5441087)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631293(CHEMBL5427932)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631287(CHEMBL5405140)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631290(CHEMBL5440017)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631295(CHEMBL5435417)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631278(CHEMBL5439582)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631288(CHEMBL5398372)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631293(CHEMBL5427932)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631277(CHEMBL5434116)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631291(CHEMBL5430795)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631279(CHEMBL5404261)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631281(CHEMBL5423387)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631297(CHEMBL5423944)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631291(CHEMBL5430795)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631288(CHEMBL5398372)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631297(CHEMBL5423944)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631295(CHEMBL5435417)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631286(CHEMBL5396523)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631293(CHEMBL5427932)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631295(CHEMBL5435417)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631286(CHEMBL5396523)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631292(CHEMBL5410919)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631296(CHEMBL5397297)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631276(CHEMBL5410927)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631297(CHEMBL5423944)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631301(CHEMBL5413771)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631285(CHEMBL5423894)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631286(CHEMBL5396523)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631283(CHEMBL5420407)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631284(CHEMBL5402123)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631290(CHEMBL5440017)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631275(CHEMBL5400756)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631293(CHEMBL5427932)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50557253(CHEMBL4742766)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
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