Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50020843
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634040(CHEMBL5437525)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634053(CHEMBL5432407)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634053(CHEMBL5432407)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634050(CHEMBL5415099)
Affinity DataIC50: 51nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634043(CHEMBL5412917)
Affinity DataIC50: 53nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634044(CHEMBL5419115)
Affinity DataIC50: 61nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634048(CHEMBL5396653)
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 70nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634052(CHEMBL5430140)
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634049(CHEMBL5420332)
Affinity DataIC50: 91nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM60812(BDBM86641 | US9173884, BC11-28)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM86639(BC11-15 | US9173884, BC11-15)
Affinity DataIC50: 180nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634051(CHEMBL5427366)
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM86642(BC11-38 | US9173884, BC11-38)
Affinity DataIC50: 280nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM60808(BDBM86640 | US9173884, BC11-19)
Affinity DataIC50: 330nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634047(CHEMBL5427158)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634041(CHEMBL5437732)
Affinity DataIC50: 580nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634046(CHEMBL5420843)
Affinity DataIC50: 630nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634042(CHEMBL5413885)
Affinity DataIC50: 890nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Mus musculus)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634053(CHEMBL5432407)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of PDE11A4 in mouse HT-22 cells assessed as reduction in cGMP hydrolytic activity using [3H]-cGMP as substrate pretreated with compound fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Mus musculus)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634053(CHEMBL5432407)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of PDE11A4 in mouse HT-22 cells assessed as reduction in cAMP hydrolytic activity using [3H]-cAMP as substrate pretreated with compound fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Mus musculus)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634043(CHEMBL5412917)
Affinity DataEC50:  4.70E+3nMAssay Description:Inhibition of PDE11A4 in mouse HT-22 cells assessed as reduction in cAMP hydrolytic activity using [3H]-cAMP as substrate pretreated with compound fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634045(CHEMBL5399341)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Mus musculus)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of PDE11A4 in mouse HT-22 cells assessed as reduction in cAMP hydrolytic activity using [3H]-cAMP as substrate pretreated with compound fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Mus musculus)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataEC50:  2.20E+4nMAssay Description:Inhibition of PDE11A4 in mouse HT-22 cells assessed as reduction in cGMP hydrolytic activity using [3H]-cGMP as substrate pretreated with compound fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Mus musculus)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50634043(CHEMBL5412917)
Affinity DataEC50:  2.20E+4nMAssay Description:Inhibition of PDE11A4 in mouse HT-22 cells assessed as reduction in cGMP hydrolytic activity using [3H]-cGMP as substrate pretreated with compound fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed