Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50020842
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634029(CHEMBL5436417)
Affinity DataEC50:  5.88E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634028(CHEMBL5432471)
Affinity DataEC50:  4.68E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634027(CHEMBL5399233)
Affinity DataEC50:  5.51E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634026(CHEMBL5440391)
Affinity DataEC50:  4.48E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634025(CHEMBL5438999)
Affinity DataEC50:  6.57E+4nMAssay Description:Inhibition of human recombinant acetylcholinesterase using acetylthiocholine as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634024(CHEBI:2942 | AZADIRACTIN)
Affinity DataEC50:  6.81E+4nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634023(CHEMBL5439936)
Affinity DataEC50:  4.69E+4nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634022(CHEMBL2296788)
Affinity DataEC50:  1.69E+4nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634023(CHEMBL5439936)
Affinity DataEC50:  2.31E+4nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634024(CHEBI:2942 | AZADIRACTIN)
Affinity DataEC50:  2.93E+4nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634022(CHEMBL2296788)
Affinity DataEC50:  4.13E+4nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 15nMAssay Description:Inhibition of COX2 (unknown origin) fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase I isoform delta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634017(CHEMBL5438108)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant CK1delta (1 to 294 residues) expressed in Escherichia coli incubated for 60 mins in presence of...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634018(CHEMBL5421148)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634017(CHEMBL5438108)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase I isoform delta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634018(CHEMBL5421148)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant CK1delta (1 to 294 residues) expressed in Escherichia coli incubated for 60 mins in presence of...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634021(CHEMBL5436499)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634018(CHEMBL5421148)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal full length human recombinant CDK5/p25 expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634033(CHEMBL5419055)
Affinity DataIC50: 768nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634016(CHEMBL5289972)
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634015(CHEMBL5421699)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal full length human recombinant CDK5/p25 expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase I isoform delta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634021(CHEMBL5436499)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant CK1delta (1 to 294 residues) expressed in Escherichia coli incubated for 60 mins in presence of...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634017(CHEMBL5438108)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of N-terminal full length human recombinant CDK5/p25 expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase I isoform delta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634016(CHEMBL5289972)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant CK1delta (1 to 294 residues) expressed in Escherichia coli incubated for 60 mins in presence of...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634019(CHEMBL5421211)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase I isoform delta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634019(CHEMBL5421211)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant CK1delta (1 to 294 residues) expressed in Escherichia coli incubated for 60 mins in presence of...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634021(CHEMBL5436499)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of N-terminal full length human recombinant CDK5/p25 expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634016(CHEMBL5289972)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of N-terminal full length human recombinant CDK5/p25 expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634015(CHEMBL5421699)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634020(CHEMBL5404645)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase I isoform delta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634020(CHEMBL5404645)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant CK1delta (1 to 294 residues) expressed in Escherichia coli incubated for 60 mins in presence of...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634014(CHEMBL5417201)
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of COX2 (unknown origin) fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634034(CHEMBL5428573)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated with compound for 15 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50559079(N-Trans-Feruloyldopamine | Trans-N-Feruloyldopamin...)
Affinity DataIC50: 8.52E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634020(CHEMBL5404645)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal full length human recombinant CDK5/p25 expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase I isoform delta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634015(CHEMBL5421699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant CK1delta (1 to 294 residues) expressed in Escherichia coli incubated for 60 mins in presence of...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634019(CHEMBL5421211)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of N-terminal full length human recombinant CDK5/p25 expressed in baculovirus-infected Sf21 cells incubated for 60 mins in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634034(CHEMBL5428573)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of JAK3 (unknown origin) preincubated for 1 hr followed by substrate addition and measured after 1 hr in the presence of ATP by FRET-based...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634035(CHEMBL5433159)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of JAK3 (unknown origin) preincubated for 1 hr followed by substrate addition and measured after 1 hr in the presence of ATP by FRET-based...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRho-associated protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634036(CHEMBL5429528)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of ROCK2 (unknown origin) incubated for 1 hr by FRET based Z'lyte assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRho-associated protein kinase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634036(CHEMBL5429528)
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of ROCK1 (unknown origin) incubated for 1 hr by FRET based Z'-lyte assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50357212(Serine | (L)-SERINE)
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate incubated for 20 mins by Ellaman's methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634032(CHEMBL5398421)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate incubated for 20 mins by Ellaman's methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634030(CHEMBL5397379)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate incubated for 20 mins by Ellaman's methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 5.46E+4nMAssay Description:Inhibition of COX1 (unknown origin) fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634031(CHEMBL5435795)
Affinity DataIC50: 5.84E+4nMAssay Description:Inhibition of Acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate incubated for 20 mins by Ellaman's methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProstaglandin G/H synthase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634014(CHEMBL5417201)
Affinity DataIC50: 7.89E+4nMAssay Description:Inhibition of COX1 (unknown origin) fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDelta-type opioid receptor(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634037(CHEMBL5426498)
Affinity DataKi:  485nMAssay Description:Binding affinity to DOR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50634038(CHEMBL5400828)
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity to alpha2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
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