Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50020358
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488779(US10961228, Example 35 | (R)-N-(3-(5-fluoro-2- (2-...)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of GST-tagged human recombinant JAK1 (866 to 1154 residues) expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488689(US10961228, Example 16 | (R)-N-(3-(2-((2-fluoro- 3...)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK1 (866 to 1154 residues) expressed in insect cells using FITC-C6-KKHTDDGYMPMSPGVA-NH peptide...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488779(US10961228, Example 35 | (R)-N-(3-(5-fluoro-2- (2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK1 (866 to 1154 residues) expressed in insect cells using FITC-C6-KKHTDDGYMPMSPGVA-NH peptide...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488685(US10961228, Example 14 | (R)-N-(3-(2-((2-fluoro- 3...)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK1 (866 to 1154 residues) expressed in insect cells using FITC-C6-KKHTDDGYMPMSPGVA-NH peptide...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50629241(CHEMBL5420468)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK1 (866 to 1154 residues) expressed in insect cells using FITC-C6-KKHTDDGYMPMSPGVA-NH peptide...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488779(US10961228, Example 35 | (R)-N-(3-(5-fluoro-2- (2-...)
Affinity DataIC50: 657nMAssay Description:Inhibition of GST-tagged human recombinant TYK2 (833 to 1187 residues) expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488779(US10961228, Example 35 | (R)-N-(3-(5-fluoro-2- (2-...)
Affinity DataIC50: 686nMAssay Description:Inhibition of GST-tagged human recombinant JAK2 (809 to 1153 residues) expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488689(US10961228, Example 16 | (R)-N-(3-(2-((2-fluoro- 3...)
Affinity DataIC50: 728nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488779(US10961228, Example 35 | (R)-N-(3-(5-fluoro-2- (2-...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488685(US10961228, Example 14 | (R)-N-(3-(2-((2-fluoro- 3...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488811(US10961228, Example 38 | (R)-N-(3-(5-fluoro-2 ((2-...)
Affinity DataIC50: 6.84E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488662(US10961228, Example 2 | (R)-N-(3-(2-(2-fluoro-3- (...)
Affinity DataIC50: 7.42E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488779(US10961228, Example 35 | (R)-N-(3-(5-fluoro-2- (2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JAK3 (781 to 1124 residues) expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50629241(CHEMBL5420468)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488662(US10961228, Example 2 | (R)-N-(3-(2-(2-fluoro-3- (...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK3 (781 to 1124 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488685(US10961228, Example 14 | (R)-N-(3-(2-((2-fluoro- 3...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK3 (781 to 1124 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488689(US10961228, Example 16 | (R)-N-(3-(2-((2-fluoro- 3...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK3 (781 to 1124 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50629241(CHEMBL5420468)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK3 (781 to 1124 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488811(US10961228, Example 38 | (R)-N-(3-(5-fluoro-2 ((2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK3 (781 to 1124 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM488779(US10961228, Example 35 | (R)-N-(3-(5-fluoro-2- (2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK3 (781 to 1124 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 peptide as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed