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Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50020207
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627700(CHEMBL5410627)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627694(CHEMBL5411166)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627699(CHEMBL5427012)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627690(CHEMBL5415222)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627698(CHEMBL5432126)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627692(CHEMBL5400043)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50507796(CHEMBL2334376)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627697(CHEMBL5412274)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627696(CHEMBL5434858)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627693(CHEMBL5425367)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627691(CHEMBL5399890)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627700(CHEMBL5410627)
Affinity DataIC50: 17nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627695(CHEMBL5409955)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627694(CHEMBL5411166)
Affinity DataIC50: 40nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627690(CHEMBL5415222)
Affinity DataIC50: 60nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627693(CHEMBL5425367)
Affinity DataIC50: 61nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627699(CHEMBL5427012)
Affinity DataIC50: 74nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627698(CHEMBL5432126)
Affinity DataIC50: 81nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627692(CHEMBL5400043)
Affinity DataIC50: 170nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627696(CHEMBL5434858)
Affinity DataIC50: 190nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627697(CHEMBL5412274)
Affinity DataIC50: 200nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627693(CHEMBL5425367)
Affinity DataIC50: 230nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627690(CHEMBL5415222)
Affinity DataIC50: 270nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627692(CHEMBL5400043)
Affinity DataIC50: 320nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627700(CHEMBL5410627)
Affinity DataIC50: 330nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627690(CHEMBL5415222)
Affinity DataIC50: 380nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627691(CHEMBL5399890)
Affinity DataIC50: 510nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627697(CHEMBL5412274)
Affinity DataIC50: 600nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627694(CHEMBL5411166)
Affinity DataIC50: 630nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627691(CHEMBL5399890)
Affinity DataIC50: 650nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627691(CHEMBL5399890)
Affinity DataIC50: 910nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627692(CHEMBL5400043)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627696(CHEMBL5434858)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627699(CHEMBL5427012)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627698(CHEMBL5432126)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627695(CHEMBL5409955)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627697(CHEMBL5412274)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627694(CHEMBL5411166)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627700(CHEMBL5410627)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627693(CHEMBL5425367)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627699(CHEMBL5427012)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627696(CHEMBL5434858)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627695(CHEMBL5409955)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627698(CHEMBL5432126)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50627695(CHEMBL5409955)
Affinity DataIC50: 5.24E+4nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed