Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50020192
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627197(CHEMBL5396628)
Affinity DataKi:  0.0130nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627203(CHEMBL5307201)
Affinity DataKi:  0.0150nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627196(CHEMBL5400376)
Affinity DataKi:  0.0180nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627201(CHEMBL5402764)
Affinity DataKi:  0.0200nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627202(CHEMBL5426737)
Affinity DataKi:  0.0200nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627200(CHEMBL5437853)
Affinity DataKi:  0.0220nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627194(CHEMBL5412641)
Affinity DataKi:  0.0230nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627193(CHEMBL5394656)
Affinity DataKi:  0.0320nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627199(CHEMBL5437622)
Affinity DataKi:  0.0340nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627192(CHEMBL5433387)
Affinity DataKi:  0.0400nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627195(CHEMBL5405517)
Affinity DataKi:  0.0410nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627198(CHEMBL5402950)
Affinity DataKi:  0.0470nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627204(CHEMBL5413705)
Affinity DataKi:  0.0600nMAssay Description:Displacement of TAMRA-labeled BIM BH3 peptide from N-terminal GST tagged human MCL-1 (171 to 327 residues) expressed in Escherichia coli assessed as ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627191(CHEMBL5403706)
Affinity DataKi:  0.0690nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM333146(US10196404, Example 1 | Compound I | US10196404, E...)
Affinity DataKi:  0.200nMAssay Description:Displacement of Fluor 647-labeled BIM peptide from N-terminal GST-tagged MCL-1 (unknown origin) assessed as inhibition constant incubated for 120 to ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627191(CHEMBL5403706)
Affinity DataKi:  11nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In DepthDetails
PubMed