Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50019548
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620396(CHEMBL5404464)
Affinity DataEC50:  7.10E+3nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Rat)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  0.310nMAssay Description:Positive allosteric modulation of rat Y4 receptor transfected with COS-7 cells assessed as activation of G-protein signaling measured after 24 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Mouse)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  0.0700nMAssay Description:Positive allosteric modulation of mouse Y4 receptor transfected with COS-7 cells assessed as activation of G-protein signaling measured after 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  1.90nMAssay Description:Positive allosteric modulation of YFP tagged human Y5 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  31nMAssay Description:Positive allosteric modulation of YFP tagged human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of YFP tagged human Y2 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  48nMAssay Description:Positive allosteric modulation of YFP tagged human Y1 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataKd:  31nMAssay Description:Displacement of K22-[TAMRA]-Nle-17,30-PP from human Nluc-Y4R transfected with COS-7 cells assessed as dissociation constant of K22-[TAMRA]-Nle-17,30-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataEC50:  125nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620395(CHEMBL5397249)
Affinity DataEC50:  1.24E+4nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620394(CHEMBL5403956)
Affinity DataEC50:  1.24E+3nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620393(CHEMBL5427179)
Affinity DataEC50:  8.52E+3nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620392(CHEMBL5441046)
Affinity DataEC50:  1.43E+4nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620391(CHEMBL5401811)
Affinity DataEC50:  2.99E+3nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620390(CHEMBL5397881)
Affinity DataEC50:  1.35E+3nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620389(CHEMBL5412071)
Affinity DataEC50:  4.52E+3nMAssay Description:Positive allosteric modulation of human Y4 receptor transfected with COS-7 cells co-transfected with delta6Galphaqi4-myr assessed as potentiation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50620388(CHEMBL5420881)
Affinity DataKi:  4.40nMAssay Description:Displacement of K22-[TAMRA]-Nle-17,30-PP from human Nluc-tagged Y4R transfected with COS-7 cells assessed as inhibition constant of pancreatic polype...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed