Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50019720
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622282(CHEMBL5433261)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622283(CHEMBL5414425)
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622271(CHEMBL5408839)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622276(CHEMBL5436336)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622275(CHEMBL5394852)
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622273(CHEMBL5427886)
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622279(CHEMBL5395024)
Affinity DataIC50: 35nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622274(CHEMBL5403771)
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622270(CHEMBL5394741)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622272(CHEMBL5407503)
Affinity DataIC50: 38nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622281(CHEMBL5406530)
Affinity DataIC50: 39nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622278(CHEMBL5417925)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622284(CHEMBL5417070)
Affinity DataIC50: 134nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622280(CHEMBL5396769)
Affinity DataIC50: 137nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622277(CHEMBL5429234)
Affinity DataIC50: 173nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT4 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NSD1 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NSD2 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MLL1 (unknown origin) using histone peptide/SAM as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MLL4 (unknown origin) using histone peptide/SAM as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9a (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GLP (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622285(CHEMBL5401398)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) using histone peptide/SAM as substrate by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed