Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019073
TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582221(CHEMBL5090028 | US11708359, Example 60 | US1197498...)
Affinity DataIC50: 0.00720nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM609871(US11708359, Example 62 | (rac)-(2s,4s)-2-(6-(4-(te...)
Affinity DataIC50: 0.0190nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582222(CHEMBL5074982 | US11708359, Example 71 | US1197498...)
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM609880(US11708359, Example 69 | (rac)-(2s,4s)-2-(6-(4-(1-...)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM609878(US11708359, Example 67 | (rac)-(2s,4s)-2-(6-(3-Chl...)
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM609885(US11708359, Example 74 | (rac)-(2s,4s)-2-(6-(4-Iso...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed