Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50002948
LigandPNGBDBM50024982(3-Hydroxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024987(3-Butoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024986(5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024984(1,2,5,6-Tetrahydro-pyridine-3-carboxylic acid meth...)
Affinity DataEC50:  300nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024980(3-But-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataEC50:  4.50E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024983(3-Benzyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024985(3-Allyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyri...)
Affinity DataEC50:  1.30E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024988(3-Methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataEC50:  1.80E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024992(3-Isopropoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]py...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024981(3-But-2-enyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM46858(cid_9301 | ARECOLINE HYDROBROMIDE | SMR000058258 |...)
Affinity DataEC50:  100nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024990(3-Propoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024989(3-(2-Bromo-allyloxy)-4,5,6,7-tetrahydro-isoxazolo[...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024996(3-Methoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataEC50:  800nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataEC50:  70nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024993(3-Ethoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataEC50:  3.40E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024979(3-Ethoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataEC50:  1.60E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024995(3-Prop-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-...)
Affinity DataEC50:  1.20E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024991(5-Ethyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataEC50:  2.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024994(3-Isobutoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024979(3-Ethoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024992(3-Isopropoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]py...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024980(3-But-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM46858(cid_9301 | ARECOLINE HYDROBROMIDE | SMR000058258 |...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024995(3-Prop-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024993(3-Ethoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024985(3-Allyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyri...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024990(3-Propoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024992(3-Isopropoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]py...)
Affinity DataIC50: 1.10E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024989(3-(2-Bromo-allyloxy)-4,5,6,7-tetrahydro-isoxazolo[...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024981(3-But-2-enyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024987(3-Butoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024991(5-Ethyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024989(3-(2-Bromo-allyloxy)-4,5,6,7-tetrahydro-isoxazolo[...)
Affinity DataIC50: 2.20E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024996(3-Methoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024984(1,2,5,6-Tetrahydro-pyridine-3-carboxylic acid meth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024983(3-Benzyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024990(3-Propoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024988(3-Methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024983(3-Benzyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50: 4.80E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024994(3-Isobutoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50: 4.90E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024986(5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024981(3-But-2-enyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024982(3-Hydroxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024994(3-Isobutoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024986(5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024987(3-Butoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024982(3-Hydroxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed