Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019362
TargetSodium channel protein type 10 subunit alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Nav1.8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 15nMAssay Description:Inhibition of Nav1.8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM186573(US9163042, 9 | US10787472, Compound 9 | US20230303...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells at -80 mV holding potential by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50618560(CHEMBL5410331)
Affinity DataIC50: 50nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells at -80 mV holding potential by whole-cell patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM186573(US9163042, 9 | US10787472, Compound 9 | US20230303...)
Affinity DataIC50: 86nMAssay Description:Inhibition of Nav1.8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50095311(CHEMBL3589904)
Affinity DataIC50: 190nMAssay Description:Inhibition of Nav1.8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed