Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50018954
TargetRibonuclease SLFN12(Human)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614155(CHEMBL4247714)
Affinity DataKd:  65nMAssay Description:Binding affinity to human recombinant SLFN12 expressed as Escherichia coli assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614155(CHEMBL4247714)
Affinity DataKd:  320nMAssay Description:Binding affinity to human recombinant PDE3B expressed as Escherichia coli assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease SLFN12(Human)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614155(CHEMBL4247714)
Affinity DataKd:  870nMAssay Description:Binding affinity to SLFN12 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614155(CHEMBL4247714)
Affinity DataKd:  40nMAssay Description:Binding affinity to PDE3A (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50000334(Agrylin | 6,7-Dichloro-1,5-dihydro-imidazo[2,1-b]q...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614155(CHEMBL4247714)
Affinity DataIC50: 25nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50027177(Cilostamide)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50000334(Agrylin | 6,7-Dichloro-1,5-dihydro-imidazo[2,1-b]q...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614154(CHEMBL5283704)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50227206(CHEMBL66522)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50228246(Indolidan)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50226407(Y-590 | CHEMBL299631)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614155(CHEMBL4247714)
Affinity DataIC50: 100nMAssay Description:Inhibition of PDE3B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50225508(CHEBI:31401 | Cilostazol | OPC-13013 | OPC-21 | Pl...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM15296(Milrinone | CHEMBL189 | 6-methyl-2-oxo-5-pyridin-4...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50227207(Quazinone | Ro-136438 | Ro-136438006)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM14769(6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydr...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50614153(CHEMBL5278813)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50241379(CHEMBL249856 | 4-Methyl-5-(4-methylsulfanyl-benzoy...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM50016980([4-(3,4-Dihydro-quinolin-6-yl)-piperazin-1-yl]-(3,...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
The Baruch S. Blumberg Institute

Curated by ChEMBL
LigandPNGBDBM34651(MLS000069829 | cid_3698 | SMR000058850 | CHEMBL128...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
PubMed