Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50018941
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614003(CHEMBL5283942)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50602410(CHEMBL5173274)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598463(CHEMBL5195325)
Affinity DataIC50: 15nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM420297(med.21724, Compound 62 | peptidomimetic aldehydes ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM420295(med.21724, Compound 67 | alpha-ketoamide inhibitor...)
Affinity DataIC50: 670nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate by FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614025(CHEMBL5290148)
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614026(CHEMBL5286093)
Affinity DataIC50: 6.47E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614012(CHEMBL5282313)
Affinity DataIC50: 6.71E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614028(CHEMBL5274265)
Affinity DataIC50: 7.48E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614029(CHEMBL5269801)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614013(CHEMBL5270638)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614027(CHEMBL5290924)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614030(CHEMBL5279877)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614024(CHEMBL5274679)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614021(CHEMBL5276507)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614020(CHEMBL5288572)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614019(CHEMBL5270863)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614016(CHEMBL5275803)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614017(CHEMBL5272656)
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614004(CHEMBL5274314)
Affinity DataIC50: 4.63E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614004(CHEMBL5274314)
Affinity DataIC50: 4.63E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614011(CHEMBL5283003)
Affinity DataIC50: 4.69E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614008(CHEMBL5285814)
Affinity DataIC50: 5.46E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614007(CHEMBL5276871)
Affinity DataIC50: 6.05E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614009(CHEMBL5269736)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614014(CHEMBL5284820)
Affinity DataIC50: 6.69E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614018(CHEMBL5290811)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614023(CHEMBL5288939)
Affinity DataIC50: 7.68E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614015(CHEMBL5277777)
Affinity DataIC50: 7.96E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614010(CHEMBL5266928)
Affinity DataIC50: 9.05E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614022(CHEMBL5280670)
Affinity DataIC50: 9.69E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614006(CHEMBL5288475)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50614005(CHEMBL5284419)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using MDA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed