Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50020765
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM150200(US8980905, 108 | US9637499, Compound 108)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660](Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50559712(CHEMBL4758412)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660](Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50559709(Lotamilast | E-6005 | E6005 | RVT-501)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50559708(CHEMBL4789722)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human full length PDE4B2 assessed as cAMP by measuring fluorescence intensity preincubated for 10 mins followed by cAMP addition furthe...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524994(CHEMBL4541964 | US11401286, Example 142)
Affinity DataIC50: 8nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660](Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50559698(CHEMBL4778157)
Affinity DataIC50: 26nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50559708(CHEMBL4789722)
Affinity DataIC50: 440nMAssay Description:Inhibition of human full length PDE4D2 assessed as cAMP by measuring fluorescence intensity preincubated for 10 mins followed by cAMP addition furthe...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660](Human)
Guangdong Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM150200(US8980905, 108 | US9637499, Compound 108)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed