Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50019830
TargetLeukotriene C4 synthase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50623420(CHEMBL5417047)
Affinity DataIC50: 2nMAssay Description:Inhibition of LTC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLeukotriene C4 synthase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50623417(CHEMBL5432381)
Affinity DataIC50: 5nMAssay Description:Inhibition of LTC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50078888(CHEMBL3416359)
Affinity DataIC50: 29nMAssay Description:Inhibition of 5-LO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50526702(CHEMBL4463974)
Affinity DataIC50: 229nMAssay Description:Inhibition of guinea pig leukotriene D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50526702(CHEMBL4463974)
Affinity DataIC50: 229nMAssay Description:Inhibition of recombinant 5-LOX (unknown origin) using H2DCFDA as substrate by measuring fluorescent 2',7'-dichlorofluorescein incubated for 35 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50000829(6-[3-Fluoro-5-(tetrahydro-pyran-4-yl)-phenoxymethy...)
Affinity DataIC50: 300nMAssay Description:Inhibition of guinea pig leukotriene D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLeukotriene C4 synthase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50623418(CHEMBL5400001)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of LTC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLeukotriene C4 synthase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50623419(CHEMBL144830)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of LTC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLeukotriene C4 synthase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50097041(1-(5-Bromo-pyridin-2-yl)-3-[2-(4-hydroxy-phenyl)-e...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of LTC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50491219(CHEMBL493720)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50133002((1H-Indol-2-yl)-piperazin-1-yl-methanone | (1H-ind...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50623416(Toreforant | Jnj-38518168 | JNJ-38518168 | TOREFOR...)
Affinity DataKi:  8.40nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50021553(CHEMBL3290570)
Affinity DataKi:  10nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50179335((5-chloro-1H-benzoimidazol-2-yl)(4-methylpiperazin...)
Affinity DataKi:  27nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50021536(CHEMBL3290576)
Affinity DataKi:  203nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50021529(CHEMBL3290578)
Affinity DataKi:  524nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed