Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50019814
TargetGTPase KRas(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50623207(CHEMBL5419780)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GTP-bound KRAS G12S mutant in human A549 cells incubated for 2 hrs by immunoblot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50623207(CHEMBL5419780)
Affinity DataKi:  2.60E+4nMAssay Description:Reversible inhibition of GDP-bound recombinant human KRAS G12S mutant assessed as inhibition constant by mass spectrometry analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50623206(CHEMBL5397483)
Affinity DataKi:  9.70E+4nMAssay Description:Reversible inhibition of GDP-bound recombinant human KRAS G12S mutant assessed as inhibition constant by mass spectrometry analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed