Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50019996
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625449(CHEMBL5424950)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM517533(USRE48711, Example 140 | 4-(4-cyclopropyl-1H-imida...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM517533(USRE48711, Example 140 | 4-(4-cyclopropyl-1H-imida...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625448(CHEMBL5400071)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625431(CHEMBL5427887)
Affinity DataIC50: 13nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625446(CHEMBL5426009)
Affinity DataIC50: 289nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625447(CHEMBL5440185)
Affinity DataIC50: 291nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625433(CHEMBL5407513)
Affinity DataIC50: 489nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625436(CHEMBL5417367)
Affinity DataIC50: 978nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625443(CHEMBL5419388)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625444(CHEMBL5399125)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625442(CHEMBL5401525)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625437(CHEMBL5395030)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625452(CHEMBL5415758)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625434(CHEMBL5417583)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625432(CHEMBL5418366)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625455(CHEMBL5437066)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625441(CHEMBL5404747)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625454(CHEMBL5435837)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625453(CHEMBL5394085)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625451(CHEMBL5414169)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625450(CHEMBL5405312)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625435(CHEMBL5439242)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50361645(CHEMBL1234429 | US9873693, Compound 144)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625438(CHEMBL5424839)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625445(CHEMBL5432766)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625439(CHEMBL5412415)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50625440(CHEMBL5421044)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant ASK1 using MBP as substrate preincubated for 1 hr followed by reagent addition incubated for 40 mins by ATP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed