Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50019812
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 47nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using pNPP as substrate in presence of 1 nM enzyme incubated for 1 hr by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 69nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using pNPP as substrate in presence of 2.5 nM enzyme incubated for 2 hrs by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 92nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 92nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate in presence of 1 nM enzyme incubated for 20 mins by fluorescence plate ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 103nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using pNPP as substrate in presence of 5 nM enzyme incubated for 3 hrs by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 135nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate in presence of 2.5 nM enzyme incubated for 20 mins by fluorescence plat...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680881(US20240199525, Compound BPDA6)
Affinity DataIC50: 216nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 237nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate in presence of 5 nM enzyme incubated for 20 mins by fluorescence plate ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM681986(US20240199525, Compound BPDA10)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680901(US20240199525, Compound BPDA9)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50623186(CHEMBL5434597)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680886(US20240199525, Compound BPDA1)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680888(US20240199525, Compound BPDA4)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50623187(CHEMBL5410478)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680887(US20240199525, Compound BPDA3)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680898(US20240199525, Compound BPDA5)
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 3.34E+4nMAssay Description:Inhibition of GST-tagged SHP1 PTP domain (unknown origin) using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680880(US20240199525, Compound BPDA2)
Affinity DataIC50: 4.07E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed