Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50019170
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant C-terminal hexahistidine tagged mature human PARL using Ac-RRRAVFLA-4mc as substrate preincubated for 1 hr followed by subs...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant C-terminal hexahistidine tagged mature human PARL using Ac-RRRAVFLA-4mc as substrate preincubated for 1 hr followed by subs...More data for this Ligand-Target Pair
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of C-terminal His-tagged full length Escherichia coli GIpG expressed in Escherichia coli C43 (DE3) using Ac-RVRHA-4mc as substrate preincu...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human PARL expressed in human HEK293T cells cotransfected human FLAG tagged PGAM5 assessed as inhibition of CCCP induced full length PG...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of tetracycline inducible FLAG tagged human PARL expressed in human PARL knockout Flp-In-T-REx-293 cells cotransfected human PGAM5-Myc ass...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of recombinant C-terminal hexahistidine tagged mature human PARL using Ac-RRRAVFLA-4mc as substrate preincubated for 1 hr followed by subs...More data for this Ligand-Target Pair
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of tetracycline inducible FLAG tagged human PARL expressed in human PARL knockout Flp-In-T-REx-293 cells cotransfected human PGAM5-Myc ass...More data for this Ligand-Target Pair
