Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 50020721
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM15908(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-di...)
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 1nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633058(CHEMBL5418449)
Affinity DataIC50: 2nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633043(CHEMBL5406554)
Affinity DataIC50: 3nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633063(CHEMBL5405404)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633060(CHEMBL5394033)
Affinity DataIC50: 5nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633066(CHEMBL5436709)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633062(CHEMBL5396572)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633064(CHEMBL5419748)
Affinity DataIC50: 7nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633067(CHEMBL5403895)
Affinity DataIC50: 8nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633042(CHEMBL5408056)
Affinity DataIC50: 10nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633061(CHEMBL5428554)
Affinity DataIC50: 24nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK2 (unknown origin) by ATP-competitive assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK1 (unknown origin) by ATP-competitive assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633058(CHEMBL5418449)
Affinity DataIC50: 44nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633063(CHEMBL5405404)
Affinity DataIC50: 44nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633055(CHEMBL5439223)
Affinity DataIC50: 55nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633066(CHEMBL5436709)
Affinity DataIC50: 56nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633060(CHEMBL5394033)
Affinity DataIC50: 66nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633067(CHEMBL5403895)
Affinity DataIC50: 81nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 90nMAssay Description:Inhibition of JNK3 (unknown origin) by ATP-competitive assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM392716(Example 10 | US10301291, Compound 11d)
Affinity DataIC50: 142nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 144nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633063(CHEMBL5405404)
Affinity DataIC50: 148nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 167nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633060(CHEMBL5394033)
Affinity DataIC50: 211nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633043(CHEMBL5406554)
Affinity DataIC50: 230nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633061(CHEMBL5428554)
Affinity DataIC50: 241nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633062(CHEMBL5396572)
Affinity DataIC50: 268nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 11(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 280nMAssay Description:Inhibition of human SAPK2b assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633064(CHEMBL5419748)
Affinity DataIC50: 287nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM392711(Example 5 | US10301291, Compound 10e)
Affinity DataIC50: 290nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 298nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 14(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 310nMAssay Description:Inhibition of human SAPK2a assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633058(CHEMBL5418449)
Affinity DataIC50: 312nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM392710(Example 4 | US10301291, Compound 10d)
Affinity DataIC50: 321nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 340nMAssay Description:Inhibition of human JNK2alpha1 assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633062(CHEMBL5396572)
Affinity DataIC50: 359nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human JNK2 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633057(CHEMBL5429268)
Affinity DataIC50: 396nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM392712(Example 6 | US10301291, Compound 10f)
Affinity DataIC50: 421nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633067(CHEMBL5403895)
Affinity DataIC50: 444nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633066(CHEMBL5436709)
Affinity DataIC50: 513nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM392717(Example 11 | US10301291, Compound 11e)
Affinity DataIC50: 611nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM392713(Example 7 | US10301291, Compound 11a)
Affinity DataIC50: 814nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 860nMAssay Description:Inhibition of human JNK1alpha1 assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633061(CHEMBL5428554)
Affinity DataIC50: 962nMAssay Description:Inhibition of human JNK1 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 970nMAssay Description:Inhibition of MKK4 (unknown origin) assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMAPK/MAK/MRK overlapping kinase(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621796(CHEMBL5396715)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of MOK (unknown origin) assessed as incorporation of 33P-ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50633056(CHEMBL5396830)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
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