Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50018684
TargetCyclin-dependent kinase 1(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 82nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611387(CHEMBL5286623)
Affinity DataIC50: 161nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 290nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human sPLA2-VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611379(CHEMBL5275045)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human sPLA2-VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611380(CHEMBL5280862)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611379(CHEMBL5275045)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611381(CHEMBL5266517)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human sPLA2-VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611382(CHEMBL5267419)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611378(CHEMBL5274868)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human sPLA2-VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611381(CHEMBL5266517)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611377(CHEMBL5278118)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human sPLA2-VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611380(CHEMBL5280862)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human sPLA2-VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611382(CHEMBL5267419)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human sPLA2-VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611378(CHEMBL5274868)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611377(CHEMBL5278118)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of ovine COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 7.34E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611381(CHEMBL5266517)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611382(CHEMBL5267419)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611380(CHEMBL5280862)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611377(CHEMBL5278118)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611378(CHEMBL5274868)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611379(CHEMBL5275045)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611385(CHEMBL5266585)
Affinity DataIC50: 2.34E+4nMAssay Description:Antagonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM18678(CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...)
Affinity DataIC50: 2.46E+4nMAssay Description:Antagonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611386(CHEMBL5286150)
Affinity DataIC50: 4.58E+4nMAssay Description:Antagonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611383(CHEMBL1596561)
Affinity DataIC50: 2.14E+5nMAssay Description:Antagonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50611384(CHEMBL5272426)
Affinity DataIC50: 4.87E+5nMAssay Description:Antagonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Prince Sattam Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50231549(CHEMBL4086946)
Affinity DataKi:  183nMAssay Description:Binding affinity to GABAA alpha1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed