Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50015680
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataKd:  21nMAssay Description:Binding affinity to human recombinant STAT3 expressed in Escherichia coli BL21 by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588528(CHEMBL5209107)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588530(CHEMBL5201151)
Affinity DataIC50: 13nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588531(CHEMBL5171007)
Affinity DataIC50: 20nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588507(CHEMBL5178622)
Affinity DataIC50: 22nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588526(CHEMBL5189135)
Affinity DataIC50: 28nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588514(CHEMBL5184385)
Affinity DataIC50: 31nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588527(CHEMBL5201419)
Affinity DataIC50: 36nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588529(CHEMBL5209399)
Affinity DataIC50: 38nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588524(CHEMBL5205645)
Affinity DataIC50: 39nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588518(CHEMBL5175035)
Affinity DataIC50: 40nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588532(CHEMBL5200170)
Affinity DataIC50: 46nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588505(CHEMBL5206754)
Affinity DataIC50: 64nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588501(CHEMBL5193538)
Affinity DataIC50: 72nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588506(CHEMBL5201590)
Affinity DataIC50: 76nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588512(CHEMBL5201252)
Affinity DataIC50: 101nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588513(CHEMBL5176872)
Affinity DataIC50: 134nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588515(CHEMBL5170042)
Affinity DataIC50: 167nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588523(CHEMBL5169762)
Affinity DataIC50: 217nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588519(CHEMBL5205634)
Affinity DataIC50: 337nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588502(CHEMBL5182559)
Affinity DataIC50: 427nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588500(CHEMBL5199129)
Affinity DataIC50: 492nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588499(CHEMBL5179803)
Affinity DataIC50: 595nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588516(CHEMBL5179525)
Affinity DataIC50: 613nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588503(CHEMBL5199213)
Affinity DataIC50: 649nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588493(CHEMBL5198840)
Affinity DataIC50: 801nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588504(CHEMBL5181349)
Affinity DataIC50: 836nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588521(CHEMBL5181464)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588522(CHEMBL5170230)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588496(CHEMBL5169741)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588494(CHEMBL5197245)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588495(CHEMBL5169452)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588497(CHEMBL5171613)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588498(CHEMBL5182652)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588508(CHEMBL5206929)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588509(CHEMBL5178714)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588510(CHEMBL5209852)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588511(CHEMBL5178178)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588517(CHEMBL5185180)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588520(CHEMBL5177234)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588492(CHEMBL5208945)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 13(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate in presence of NADPH by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
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