Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50018799
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612685(CHEMBL5283866)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human PRMT5 by fluorescence-based SAHH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50462572(CHEMBL4249337)
Affinity DataIC50: 0.772nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612685(CHEMBL5283866)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human PRMT4 by fluorescence-based SAHH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM415556(US10428104, Example 87)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612684(CHEMBL5281295)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50366992(CHEMBL4168754)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM177922(US9675614, 166 | US10307413, Compound 337 | US1039...)
Affinity DataIC50: 22nMAssay Description:Inhibition of PRMT5 human PRMT5 using [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612672(CHEMBL5281980)
Affinity DataIC50: 330nMAssay Description:Inhibition of PRMT5 human PRMT5 using Biotinylated H4 derived peptide and [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612680(CHEMBL5280377)
Affinity DataIC50: 720nMAssay Description:Inhibition of PRMT5 human PRMT5 using [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612682(CHEMBL5281105)
Affinity DataIC50: 770nMAssay Description:Inhibition of human PRMT5 using H4R3 S1ac and [3H]-SAM as substrate by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612670(CHEMBL2094306 | DNDI1388323)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PRMT5 human PRMT5 using Biotinylated H4 derived peptide and [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612687(CHEMBL5278223)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human PRMT1 by fluorescence-based SAHH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612679(CHEMBL5279471)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PRMT5 human PRMT5 using [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612686(CHEMBL5266117)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human PRMT1 by fluorescence-based SAHH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612677(CHEMBL5281797)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of PRMT5 human PRMT5 using [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612669(CHEMBL497024)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of PRMT5 human PRMT5 using Biotinylated H4 derived peptide and [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612671(CHEMBL575927)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of PRMT5 human PRMT5 using Biotinylated H4 derived peptide and [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612685(CHEMBL5283866)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human PRMT1 by fluorescence-based SAHH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612675(CHEMBL5271163)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PRMT5 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612683(CHEMBL5266665)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human PRMT5 using H4R3 S1ac and [3H]-SAM as substrate by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612674(CHEMBL5267041)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of PRMT5 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612682(CHEMBL5281105)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PRMT1 using H4R3 S1ac and [3H]-SAM as substrate by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612681(CHEMBL5282043)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human PRMT5 using H4R3 S1ac and [3H]-SAM as substrate by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612676(CHEMBL5278276)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612678(CHEMBL5276294)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of PRMT5 human PRMT5 using [3H]-SAM as substrate by radioactive methylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50506820(CHEMBL4513282)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as enzymatic activity by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50612673(CHEMBL5274956)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed