Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50018047
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607229(CHEMBL5219235)
Affinity DataEC50:  0.430nMAssay Description:Agonist activity at human CB1 receptor expressed in mouse AtT20 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607248(CHEMBL5221091)
Affinity DataEC50:  87nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607247(CHEMBL5219080)
Affinity DataEC50:  484nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607246(CHEMBL5219313)
Affinity DataEC50:  101nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607245(CHEMBL5220917)
Affinity DataEC50:  157nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607244(CHEMBL5220316)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607243(CHEMBL5220552)
Affinity DataEC50:  166nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607242(CHEMBL5219090)
Affinity DataEC50:  490nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607241(CHEMBL5220484)
Affinity DataEC50:  759nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607240(CHEMBL5220838)
Affinity DataEC50:  174nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50194613(CHEMBL3947764)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607239(CHEMBL5218533)
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607238(CHEMBL5221103)
Affinity DataKd:  690nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607237(CHEMBL5219769)
Affinity DataKd:  140nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607236(CHEMBL5220693)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607228(CHEMBL5220222)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human CB1 receptor expressed in mouse AtT20 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607230(CHEMBL5218844)
Affinity DataEC50:  4.70nMAssay Description:Agonist activity at human CB1 receptor expressed in mouse AtT20 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607228(CHEMBL5220222)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human CB2 receptor expressed in mouse AtT20 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607229(CHEMBL5219235)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human CB2 receptor expressed in mouse AtT20 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607230(CHEMBL5218844)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human CB2 receptor expressed in mouse AtT20 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50086260(CHEMBL3425846)
Affinity DataKd:  52nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607231(CHEMBL5221079)
Affinity DataKd:  360nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607232(CHEMBL5219940)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607233(CHEMBL5220952)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607234(CHEMBL5218560)
Affinity DataKd:  620nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607235(CHEMBL5220364)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50507725(CHEMBL4576567)
Affinity DataKd:  770nMAssay Description:Binding affinity to GAK (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50303527((2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluor...)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membrane incubated for 1 hr by liquid scintillation spectrophotometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50008984(N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionami...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor measured after 2 hrs by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DAMGO from human cloned mu-opioid receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50303527((2,2,3,3-Tetramethylcyclopropyl)(1-(4,4,4-trifluor...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membrane incubated for 1 hr by liquid scintillation spectrophotometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50607249(CHEMBL5219510)
Affinity DataKi:  820nMAssay Description:Displacement of [3H]DAMGO from human cloned mu-opioid receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed