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Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50016176
TargetHistone deacetylase 6(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 20nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592935(CHEMBL5192285)
Affinity DataIC50: 30nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC8 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592937(CHEMBL5195044)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592936(CHEMBL5177837)
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592931(CHEMBL5194009)
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 70nMAssay Description:Inhibition of full length recombinant C-terminal GST-tagged human HDAC1 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC in human MDA-MB-231 cells incubated for 45 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 4(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 300nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC4 (612 to end residues)expressed in baculovirus infected Sf9 insect cells incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 330nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC8 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592935(CHEMBL5192285)
Affinity DataIC50: 650nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592935(CHEMBL5192285)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HDAC in human MDA-MB-231 cells incubated for 45 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592935(CHEMBL5192285)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of full length recombinant C-terminal GST-tagged human HDAC1 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592932(CHEMBL5178592)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592933(CHEMBL5182900)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592938(CHEMBL5192913)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592935(CHEMBL5192285)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592934(CHEMBL5208773)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592939(CHEMBL5196416)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592935(CHEMBL5192285)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human HDAC4 (612 to end residues)expressed in baculovirus infected Sf9 insect cells incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592941(CHEMBL5185730)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592942(CHEMBL5182878)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592940(CHEMBL5172555)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592943(CHEMBL4096378)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC in human MDA-MB-231 cells incubated for 45 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed