Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50016348
TargetBromodomain-containing protein 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297163(US10112941, Example 279 | 2-{8-Fluoro-3-[4-(2H3)me...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of BRD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297236(US10112941, Example 354 | 2-[3-(Dimethyl-1H-1,2,3-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297070(US10112941, Example 177 | 5-{7-Methanesulfonyl-5-[...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297163(US10112941, Example 279 | 2-{8-Fluoro-3-[4-(2H3)me...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297144(US10112941, Example 260 | 2-[3-(Dimethyl-1H-1,2,3-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM296964(2-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-6-fluoro-5-[...)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM296947(US10112941, Example 54 | 2-[3-(Dimethyl-1H-1,2,3-t...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297268(US10112941, Example 393 | 2-{6-Chloro-3-[4-(2H3)me...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM296947(US10112941, Example 54 | 2-[3-(Dimethyl-1H-1,2,3-t...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50594425(CHEMBL5189057)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297163(US10112941, Example 279 | 2-{8-Fluoro-3-[4-(2H3)me...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of BRD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297070(US10112941, Example 177 | 5-{7-Methanesulfonyl-5-[...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297283(US10112941, Example 409 | 2-[8-Chloro-3-(dimethyl-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297312(US10112941, Example 441 | 2-[3-(Dimethyl-1H-1,2,3-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50594424(CHEMBL5172933)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297244(US10112941, Example 369 | 2-[3-(Dimethyl-1H-1,2,3-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human BRD4 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) incubated for 60 mins by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed