Compile Data Set for Download or QSAR
Report error Found 196 Enz. Inhib. hit(s) with all data for entry = 50017995
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606824(CHEMBL5219841)
Affinity DataIC50: 0.209nMAssay Description:Binding affinity to AChE (unknown origin) assessed as inhibition constant using acetylthiocholine iodide as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10692(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10693(CHEMBL189957 | 3-{[methyl({7-[(9-oxo-9H-xanthen-3-...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606813(CHEMBL5220283)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of recombinant human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606816(CHEMBL5219771)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of recombinant human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606815(CHEMBL5218632)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of recombinant human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50234795(CHEMBL4089082)
Affinity DataIC50: 1nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50386421(CHEMBL2047525)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606814(CHEMBL5218900)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606831(CHEMBL5220375)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [14C]-ethanolamine from FAAH derived from rat brain membrane fraction preincubated for 20 mins followed by susbstrate addition by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50312905(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606830(CHEMBL5218447)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [14C]-ethanolamine from FAAH derived from rat brain membrane fraction preincubated for 20 mins followed by susbstrate addition by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCarboxylic ester hydrolase(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606791(CHEMBL205231 | CHEBI:8188)
Affinity DataIC50: 4nMAssay Description:Inhibition of human erythrocyte AChE using acetyl-(beta-methyl)thiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606824(CHEMBL5219841)
Affinity DataIC50: 4.5nMAssay Description:Binding affinity to human CA1 assessed as inhibition constant using p-nitrophenylacetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50292573((2-Ethyl-phenyl)-carbamic acid (3aS,8aS)-1,3a,8-tr...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of Pacific electric ray AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606824(CHEMBL5219841)
Affinity DataIC50: 4.90nMAssay Description:Binding affinity to human CA2 assessed as inhibition constant using p-nitrophenylacetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 6nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606785(CHEMBL204895)
Affinity DataIC50: 6nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50175503(Dimethyl-carbamic acid (R)-2-methyl-1-[2-(4-nitro-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606830(CHEMBL5218447)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606791(CHEMBL205231 | CHEBI:8188)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human plasma BChE using S-butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606832(CHEMBL5219522)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured upto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606798(CHEMBL5218756)
Affinity DataIC50: 7nMAssay Description:Inhibition of equine BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606806(CHEMBL5219352)
Affinity DataIC50: 7nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Bovine)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50400030(CHEMBL2177713)
Affinity DataIC50: 8nMAssay Description:Inhibition of bovine AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10725(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human erythrocyte AChE using acetyl-(beta-methyl)thiocholine as substrate by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50175503(Dimethyl-carbamic acid (R)-2-methyl-1-[2-(4-nitro-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606804(CHEMBL5221005)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606803(CHEMBL5220031)
Affinity DataIC50: 15nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606839(CHEMBL5220695)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 (unknown origin) using A-beta-PP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606840(CHEMBL5219239)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 (unknown origin) using A-beta-PP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 16nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606793(CHEMBL5221034)
Affinity DataIC50: 17nMAssay Description:Inhibition of equine BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606805(CHEMBL5219813)
Affinity DataIC50: 17nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10784(1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl ...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50238212(CHEMBL4077952)
Affinity DataIC50: 20nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50161786((4-Isopropyl-phenyl)-carbamic acid 1-methyl-8,10-d...)
Affinity DataIC50: 22nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606793(CHEMBL5221034)
Affinity DataIC50: 22nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606787(CHEMBL426674)
Affinity DataIC50: 23nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606786(CHEMBL206642)
Affinity DataIC50: 27nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10794(1-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50: 27nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 28nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10725(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606814(CHEMBL5218900)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606831(CHEMBL5220375)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50606785(CHEMBL204895)
Affinity DataIC50: 36nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50175500((S)-4-(1-(methylamino)-3-(4-nitrophenoxy)propyl)ph...)
Affinity DataIC50: 42nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
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