Compile Data Set for Download or QSAR
Report error Found 146 Enz. Inhib. hit(s) with all data for entry = 50018115
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM126500(US8778951, 310 | US11591322, Compound NVP-2)
Affinity DataIC50: 0.514nMAssay Description:Inhibition of CDK9 (unknown origin) by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-C(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM8131(N-[4-(propan-2-yl)phenyl]-4-{pyrazolo[1,5-a]pyrida...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) by LanthaScreen binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM167699(US9073922, 186 | US9796708, Example 186)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CDK9 (unknown origin) by LANCE ULight TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 7(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to CDK7 (unknown origin) by KINOMEscan methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK1/cyclin B1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404385(CHEMBL5273069)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human CDK4/Cyclin D3 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM354126(trans-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CDK9 (unknown origin) by LANCE ULight TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM8131(N-[4-(propan-2-yl)phenyl]-4-{pyrazolo[1,5-a]pyrida...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CDK19/Cyclin C (unknown origin) by LanthaScreen binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50553480(CHEMBL4741442)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50: 4nMAssay Description:Binding affinity to CDK9 (unknown origin) by KINOMEscan methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50553480(CHEMBL4741442)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM106950(US8592581, 1)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50593922(CHEMBL5199065)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK9 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404385(CHEMBL5273069)
Affinity DataIC50: 7nMAssay Description:Inhibition of human CDK9/cyclin T1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404387(CHEMBL5287128)
Affinity DataIC50: 7nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404387(CHEMBL5287128)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 7(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 7(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404387(CHEMBL5287128)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50553488(CHEMBL4743691)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full length CDK9/cyclin T1 expressed in sf9 cells preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 8(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 4(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM167699(US9073922, 186 | US9796708, Example 186)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK4 (unknown origin) by LANCE ULight TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 4(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM354126(trans-4-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK4 (unknown origin) by LANCE ULight TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404388(RIVICICLIB | Riviciclib | P 276-00 free base | P-2...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CDK9/cyclin T1 in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-K(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM8131(N-[4-(propan-2-yl)phenyl]-4-{pyrazolo[1,5-a]pyrida...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9/Cyclin K (unknown origin) by LanthaScreen binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 5(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM106950(US8592581, 1)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 7(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404387(CHEMBL5287128)
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM106950(US8592581, 1)
Affinity DataIC50: 26nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404386(CHEMBL5287796)
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 34nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50013510(CHEMBL3263773)
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubate...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of GST tagged human CDK2/Cyclin E expressed in baculovirus expression system assessed as substrate phosphorylation incubated for 45 mins u...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50553480(CHEMBL4741442)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404389(CHEMBL5285499)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK9 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 6(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
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