Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50015747
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589275(CHEMBL5190333)
Affinity DataIC50: 4nMAssay Description:Inhibition of rat liver microsomal SRD5A2 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589273(CHEMBL5182135)
Affinity DataIC50: 14nMAssay Description:Inhibition of human prostate SRD5A1 incubated for 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589274(CHEMBL5188574)
Affinity DataIC50: 14nMAssay Description:Inhibition of human prostate SRD5A1 incubated for 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589273(CHEMBL5182135)
Affinity DataIC50: 27nMAssay Description:Inhibition of SRD5A2 in HEK293 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589274(CHEMBL5188574)
Affinity DataIC50: 35nMAssay Description:Inhibition of SRD5A2 in HEK293 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50462940(CHEMBL4244937)
Affinity DataIC50: 127nMAssay Description:Inhibition of rat liver microsomal SRD5A2 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50462940(CHEMBL4244937)
Affinity DataIC50: 290nMAssay Description:Inhibition of rat liver microsomal SRD5A1 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589275(CHEMBL5190333)
Affinity DataIC50: 320nMAssay Description:Inhibition of rat liver microsomal SRD5A1 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589272(CHEMBL5197695)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 30 mins followed by GTP addition by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589271(CHEMBL5195501)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 30 mins followed by GTP addition by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589270(CHEMBL5197342)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 30 mins followed by GTP addition by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTubulin beta chain(Pig)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50589269(CHEMBL5190050)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 30 mins followed by GTP addition by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed