Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 50017279
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  53nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600706(CHEMBL5190997)
Affinity DataEC50:  66nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600707(CHEMBL5205123)
Affinity DataEC50:  152nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600708(CHEMBL5191475)
Affinity DataEC50:  299nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600709(CHEMBL5184707)
Affinity DataEC50:  118nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600710(CHEMBL5196639)
Affinity DataEC50:  142nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600711(CHEMBL5203086)
Affinity DataEC50:  111nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600712(CHEMBL5169696)
Affinity DataEC50:  57nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600713(CHEMBL5187016)
Affinity DataEC50:  27nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600714(CHEMBL5174082)
Affinity DataEC50:  92nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600715(CHEMBL5178176)
Affinity DataEC50:  95nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600716(CHEMBL5174333)
Affinity DataEC50:  59nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600717(CHEMBL5204574)
Affinity DataEC50:  538nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600718(CHEMBL5201654)
Affinity DataEC50:  919nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600719(CHEMBL5181899)
Affinity DataEC50:  25nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600720(CHEMBL5189418)
Affinity DataEC50:  44nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600721(CHEMBL5184419)
Affinity DataEC50:  149nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600722(CHEMBL5205416)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600723(CHEMBL5204648)
Affinity DataEC50:  1.09E+3nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600724(CHEMBL5199184)
Affinity DataEC50:  114nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM538213(US11254663, Example 10)
Affinity DataEC50:  228nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600725(CHEMBL5180682)
Affinity DataEC50:  93nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600726(CHEMBL5172239)
Affinity DataEC50:  70nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM538277(US11254663, Example 119)
Affinity DataEC50:  29nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM538299(US11254663, Example 157)
Affinity DataEC50:  45nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM538513(US11254663, Example 440)
Affinity DataEC50:  104nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600727(CHEMBL5177647)
Affinity DataEC50:  41nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600728(CHEMBL5189617)
Affinity DataEC50:  170nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600729(CHEMBL5208567)
Affinity DataEC50:  232nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600730(CHEMBL5173549)
Affinity DataEC50:  111nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600731(CHEMBL5178315)
Affinity DataEC50:  152nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600732(CHEMBL5202191)
Affinity DataEC50:  25nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  34nMAssay Description:Agonist activity at Gal4-fused human FXR in HEK293 cells incubated for 15 min by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  351nMAssay Description:Agonist activity at LBD fused human FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  42nMAssay Description:Agonist activity at LBD fused human FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Mouse)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  320nMAssay Description:Agonist activity at mouse LBD fused FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBile acid receptor(Mouse)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mouse LBD fused FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  281nMAssay Description:Agonist activity at human FXR2 expressed in Huh-7 cells coexpressing BSEP relative to GW2064More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50: >4.00E+4nMAssay Description:Agonist activity at human FXR2 expressed in Huh-7 cells coexpressing BSEP relative to GW2064More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human FXR2 expressed in HEK293 cells coexpressing human FGF19 incubated for 24 hrs by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  191nMAssay Description:Agonist activity at human FXR2 expressed in HEK293 cells coexpressing human FGF19 incubated for 24 hrs by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human FXR2 expressed in HEK293 cells coexpressing IBABPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human FXR2 expressed in HEK293 cells coexpressing IBABPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  243nMAssay Description:Agonist activity at human FXR2 expressed in Huh-7 cells coexpressing BSEPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRNA-binding protein FXR2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  389nMAssay Description:Agonist activity at human FXR2 expressed in Huh-7 cells coexpressing BSEPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600720(CHEMBL5189418)
Affinity DataEC50:  6.00E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600721(CHEMBL5184419)
Affinity DataEC50:  8.00E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600722(CHEMBL5205416)
Affinity DataEC50:  5.00E+4nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600723(CHEMBL5204648)
Affinity DataEC50:  4.00E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Center

Curated by ChEMBL
LigandPNGBDBM50600724(CHEMBL5199184)
Affinity DataEC50:  2.00E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
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