Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50016090
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of N-terminal FLAG-tagged human Clk1 using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592247(CHEMBL5200367)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRSR peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592247(CHEMBL5200367)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRSR peptide as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592235(CHEMBL5205505)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592236(CHEMBL5206943)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant GST tagged full length CLK4 expressed in Baculovirus expression system at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592248(CHEMBL5178079)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant Clk1 (130 to end residues) using ERMRPRKRQGSVR peptide as substrate incubated for 40 mins in presence of [gamma 32P-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592236(CHEMBL5206943)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592248(CHEMBL5178079)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant Clk4 (128 to end residues) using YRRAAVPPSPSLS peptide as substrate incubated for 40 mins in presence of [gamma 32P-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Mouse)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Dyrk1A expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592249(CHEMBL5191395)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRSR peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal FLAG-tagged human Clk2 using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Mouse)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk4 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592237(CHEMBL5172542)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592248(CHEMBL5178079)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant Clk2 (138 to end residues) using YRRAAVPPSPSLSR peptide as substrate incubated for 40 mins in presence of [gamma 32P-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk1 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592238(CHEMBL5191525)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592239(CHEMBL5183331)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592240(CHEMBL5177305)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592241(CHEMBL5206862)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592242(CHEMBL5174345)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592243(CHEMBL5181998)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592244(CHEMBL5194284)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592245(CHEMBL5200302)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592249(CHEMBL5191395)
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRSR peptide as substrate in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Mouse)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50026622(CHEMBL408982)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk2 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592248(CHEMBL5178079)
Affinity DataIC50: 213nMAssay Description:Inhibition of human recombinant full length DYRK1A using RRRFRPASPLRGPP peptide as substrate incubated for 40 mins in presence of [gamma 32P-ATP] and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592238(CHEMBL5191525)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRS peptide as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592237(CHEMBL5172542)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRS peptide as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592242(CHEMBL5174345)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRS peptide as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592235(CHEMBL5205505)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRS peptide as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50: 260nMAssay Description:Inhibition of N-terminal FLAG-tagged human DYRK1A using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592249(CHEMBL5191395)
Affinity DataIC50: 355nMAssay Description:Inhibition of human recombinant GST tagged full length DYRK1A expressed in Baculovirus expression system using GRSRSRSRSRSRSRSR peptide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592236(CHEMBL5206943)
Affinity DataIC50: 486nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRS peptide as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed