Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50017905
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605987(CHEMBL5185575)
Affinity DataIC50: 504nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606010(CHEMBL5189833)
Affinity DataIC50: 561nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as inhibition of relaxin-3 stimulated ERK1/2 phosphorylation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606008(CHEMBL5169478)
Affinity DataIC50: 1.49E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605998(CHEMBL5177617)
Affinity DataIC50: 2.12E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606002(CHEMBL5207177)
Affinity DataIC50: 2.12E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606007(CHEMBL5184518)
Affinity DataIC50: 2.67E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606010(CHEMBL5189833)
Affinity DataIC50: 3.04E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding incubated for 1 hr by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606009(CHEMBL5207128)
Affinity DataIC50: 3.08E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606004(CHEMBL5191322)
Affinity DataIC50: 4.04E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606000(CHEMBL5177224)
Affinity DataIC50: 4.34E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606009(CHEMBL5207128)
Affinity DataIC50: 4.52E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding incubated for 1 hr by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606001(CHEMBL5202737)
Affinity DataIC50: 4.72E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605988(CHEMBL5174194)
Affinity DataIC50: 4.78E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding incubated for 1 hr by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605994(CHEMBL5173667)
Affinity DataIC50: 4.95E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605999(CHEMBL5177511)
Affinity DataIC50: 5.28E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605988(CHEMBL5174194)
Affinity DataIC50: 5.74E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606006(CHEMBL5174579)
Affinity DataIC50: 6.13E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605990(CHEMBL5182611)
Affinity DataIC50: 6.98E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606003(CHEMBL5170512)
Affinity DataIC50: 7.69E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605989(CHEMBL5208662)
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605987(CHEMBL5185575)
Affinity DataIC50: 7.82E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as inhibition of relaxin-3 stimulated ERK1/2 phosphorylation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605996(CHEMBL5191162)
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605995(CHEMBL5170646)
Affinity DataIC50: 8.51E+3nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605997(CHEMBL5178422)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606005(CHEMBL5202616)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605993(CHEMBL5205829)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605992(CHEMBL5183768)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605991(CHEMBL5197121)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606009(CHEMBL5207128)
Affinity DataIC50: 1.39E+4nMAssay Description:Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as inhibition of relaxin-3 stimulated ERK1/2 phosphorylation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRelaxin-3 receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50605987(CHEMBL5185575)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]R3/I5 from human RXFP3 expressed in CHO-K1 cells membrane assessed as inhibition constant incubated for 1 hr by microplate scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50606009(CHEMBL5207128)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of sigma-2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed