Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50015891
TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of cathepsin L (unknown origin) using Cbz-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCathepsin B(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of cathepsin B (unknown origin) using Cbz-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 300nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant Staphylococcus aureus sortase A deltaN24 transpeptidation expressed in Escherichia coli BL21 (DE3) cells using Abz-LPATG-Dn...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 400nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 500nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 1.10E+3nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus sortase A deltaN24 transpeptidation expressed in Escherichia coli BL21 (DE3) cells using IsdA64 to 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataKi:  2.45E+3nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed