Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50016260
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593628(CHEMBL5197192)
Affinity DataKd:  440nMAssay Description:Binding affinity to ARC4 domain at TNKS2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593629(CHEMBL5173796)
Affinity DataKd:  600nMAssay Description:Binding affinity to ARC4 domain at TNKS2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593630(CHEMBL1408855)
Affinity DataKd:  1.05E+6nMAssay Description:Binding affinity to ARC4 domain at TNKS2 (unknown origin) assessed as dissociation constant by NMR titration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593630(CHEMBL1408855)
Affinity DataKd:  1.20E+6nMAssay Description:Binding affinity to ARC4 domain at TNKS2 (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 - 1327 residues) (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST-tagged TNKS2 (873 - 1166 residues) (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse recombinant PARP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593624(CHEMBL5206816)
Affinity DataIC50: 1nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593624(CHEMBL5206816)
Affinity DataIC50: 2nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593625(CHEMBL5190651)
Affinity DataIC50: 3nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593624(CHEMBL5206816)
Affinity DataIC50: 5nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593625(CHEMBL5190651)
Affinity DataIC50: 9nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataIC50: 11nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511566(CHEMBL4448872)
Affinity DataIC50: 11nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 12nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511566(CHEMBL4448872)
Affinity DataIC50: 14nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593626(CHEMBL4303453)
Affinity DataIC50: 15nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50522320(CHEMBL4454483)
Affinity DataIC50: 19nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50522320(CHEMBL4454483)
Affinity DataIC50: 21nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511548(CHEMBL4449082)
Affinity DataIC50: 36nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511548(CHEMBL4449082)
Affinity DataIC50: 39nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant TNKS2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant TNKS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50: 52nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 56nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50: 67nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataIC50: 114nMAssay Description:Inhibition of PAPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 131nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 200nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50019166(CHEMBL336718)
Affinity DataIC50: 290nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50380592(CHEMBL1552719)
Affinity DataIC50: 650nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50: 928nMAssay Description:Inhibition of PARP1 (unknown origin) by fluorescence based multimode plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511548(CHEMBL4449082)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of PAPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50522320(CHEMBL4454483)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of PAPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50380592(CHEMBL1552719)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511566(CHEMBL4448872)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of PAPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50468269(CHEMBL4285233)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of PARP1 (unknown origin) at 10 uM relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007582(CHEMBL3238252)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50593625(CHEMBL5190651)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511548(CHEMBL4449082)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of PAPR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50007583(CHEMBL562310 | CHEBI:62882)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50511566(CHEMBL4448872)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50522320(CHEMBL4454483)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed