Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50016054
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of mouse GAT-1 assessed as inhibition of GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of mouse GAT-1 assessed as inhibition of GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of mouse GAT-1 expressed in human HEK293 cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Inhibition of mouse GAT-1 expressed in human HEK293 cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human GAT-3 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of mouse GAT-4 assessed as inhibition of [3H]GABA uptake by liquid scintillation counter methodMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of rat GAT-2 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.47E+4nMAssay Description:Inhibition of mouse GAT-1 expressed in human HEK293 cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.25E+4nMAssay Description:Inhibition of mouse GAT-2 expressed in human HEK293 cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7.24E+4nMAssay Description:Inhibition of mouse GAT-1 expressed in human HEK293 cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse GAT-2 expressed in human HEK293 cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Human)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human BGT-1 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human GAT-1 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Binding affinity to mouse GAT-1 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 8.90nMAssay Description:Binding affinity to mouse GAT-1 assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of [3H]-GABA uptake at GAT-1 in rat forebrain synaptosomes assessed as inhibition constant preincubated for 8 mins followed by [3H]-GABA a...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Binding affinity to mouse GAT-1 expressed in human HEK293 cells assessed as inhibition constant in presence of NO711 marker by competitive binding as...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Isf College of Pharmacy
Curated by ChEMBL
Isf College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Binding affinity to mouse GAT-1 expressed in human HEK293 cells assessed as inhibition constant in presence of NO711 marker by competitive binding as...More data for this Ligand-Target Pair
