Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50016446
TargetEpidermal growth factor receptor(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595013(CHEMBL5201532)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of EGFR (unknown origin) using poly (glu-tyr) as substrate incubated for 1 hr in presence of ATP measured by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595018(CHEMBL5208027)
Affinity DataIC50: 21nMAssay Description:Inhibition of horse serum BuChE preincubated for 5 mins followed by BuCh addition measured after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 26nMAssay Description:Inhibition of EGFR (unknown origin) using poly (glu-tyr) as substrate incubated for 1 hr in presence of ATP measured by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595018(CHEMBL5208027)
Affinity DataIC50: 79nMAssay Description:Inhibition of AChE (unknown origin) preincubated for 5 mins followed by BuCh addition measured after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595014(CHEMBL4551230)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595015(CHEMBL4456516)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595016(CHEMBL4469807)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595018(CHEMBL5208027)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of human serum BuChE preincubated for 5 mins followed by BuCh addition measured after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595018(CHEMBL5208027)
Affinity DataKi:  29nMAssay Description:Binding affinity to BuChE (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAutotaxin(Human)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595017(CHEMBL3606084)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity to autotaxin (unknown origin) phosphodiesterase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed