Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with all data for entry = 50015358
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585811(CHEMBL5082142)
Affinity DataIC50: 620nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585797(CHEMBL5070403)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 810nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of alpha7 nicotinic acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585810(CHEMBL5081505)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585795(CHEMBL5087754)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585798(CHEMBL5085636)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585794(CHEMBL5079518)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50315305((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-amin...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585806(CHEMBL5085511)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585791(CHEMBL5079671)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585810(CHEMBL5081505)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50315305((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-amin...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50315305((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-amin...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585807(CHEMBL5077132)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585808(CHEMBL5083458)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585807(CHEMBL5077132)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585810(CHEMBL5081505)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585789(CHEMBL5086715)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585810(CHEMBL5081505)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585802(CHEMBL5082441)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585803(CHEMBL5080863)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585808(CHEMBL5083458)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585811(CHEMBL5082142)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of alpha7 nicotinic acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585808(CHEMBL5083458)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585811(CHEMBL5082142)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50315305((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-amin...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585796(CHEMBL5092098)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585799(CHEMBL5079186)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585805(CHEMBL5093818)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585788(CHEMBL5070958)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585804(CHEMBL5078032)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
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