Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50017122
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599913(CHEMBL5200023)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599911(CHEMBL5205697)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599912(CHEMBL5209381)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599907(CHEMBL5195091)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599901(CHEMBL5176374)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599902(CHEMBL5193798)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599917(CHEMBL5172819)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599910(CHEMBL5196828)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599906(CHEMBL5173624)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 1.10E+5nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataIC50: 6.30E+5nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  0.300nMAssay Description:Modulation of human D2L receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50443101(Cariprazine | RGH-188)
Affinity DataKi:  0.501nMAssay Description:Modulation of human D2L receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi:  4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599917(CHEMBL5172819)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599903(CHEMBL5182877)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599915(CHEMBL5170927)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599909(CHEMBL5188923)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599903(CHEMBL5182877)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599907(CHEMBL5195091)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599913(CHEMBL5200023)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599910(CHEMBL5196828)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599911(CHEMBL5205697)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599904(CHEMBL5178994)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599908(CHEMBL5178688)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599912(CHEMBL5209381)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599901(CHEMBL5176374)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599914(CHEMBL5202003)
Affinity DataKi:  860nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599911(CHEMBL5205697)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599902(CHEMBL5193798)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599907(CHEMBL5195091)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599913(CHEMBL5200023)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599905(CHEMBL5173564)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599916(CHEMBL5201798)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599909(CHEMBL5188923)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Czech Republic

Curated by ChEMBL
LigandPNGBDBM50599903(CHEMBL5182877)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
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