Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50015264
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM403460(US10335399, Example 2-5 | US10806724, Example 2-5)
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM393885(US9969726, Example 182 | US10597367, Example 182)
Affinity DataIC50: 8.30nMAssay Description:Negative allosteric modulator activity at human recombinant mGlur2 expressed in HEK293 cells by calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50584759(CHEMBL5089623)
Affinity DataIC50: 93nMAssay Description:Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50584759(CHEMBL5089623)
Affinity DataIC50: 93nMAssay Description:Negative allosteric modulation activity at human recombinant mGlur2 expressed in CHO cells in presence of cAMP by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM403460(US10335399, Example 2-5 | US10806724, Example 2-5)
Affinity DataKi:  59nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM403460(US10335399, Example 2-5 | US10806724, Example 2-5)
Affinity DataKi:  59nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50584759(CHEMBL5089623)
Affinity DataKi:  63nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50584759(CHEMBL5089623)
Affinity DataKi:  63nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed